Oh, I recall some crazy situations that people could do with a mouse on others. I can get away with not talking about the detestable act because it's not necessary for the verse, so I'm still having my fun of making this PG-rated at the worst. People doing that detestable act with the mouse would definitely mean they are defiling themselves.
By consecrating ourselves with the Lord, I think at the moment that it's referring to how it's about making ourselves right with God. A verse in the New Testament says that we are made righteous from putting our faith in Christ. In this verse, even though I wouldn't fully understand what God is commanding us to do, I think it's about keeping an obedient spirit. Of course, people at the top would want servants who are loyal, trustworthy, and obedient.
The thing about God though is that He knows we don't fully follow His commands, and He doesn't fire us from our relationship with Him. God is totally on a more surpassed level than us, beyond understanding. It's because God sees Jesus through His believers and that's why He's able to forgive them for it. The Bible mentions about how God is a patient and loving God that He continues to parry, wishing none would perish as a non-believing sinner. The thing about it though is that a lot of this is pretty much in the Bible, so there wouldn't be good enough material so far to contradict the existence of God, based on the book alone. It's because these books have a steady flow of consistency like it can fit logically as well from a scholarly point.
There were books like the Apocrypha, but they are with uncertain origins and also do not fit in with the rest of the books, but the books that are in today's Holy Bible all fit together after having been written for several millennium, which is cool for making comparisons with.